Figure 1From: Multiple types of data are required to identify the mechanisms influencing the spatial expansion of melanoma cell coloniesCell motility, cell–to–cell adhesion and cell proliferation mechanisms drive cell colony expansion. Schematic representation of the circular barrier assay illustrating the mechanisms influencing the expansion of a two–dimensional cell colony. Cells are placed inside the barrier which is lifted at t=0 hours allowing the colony of cells to expand outwards until t=48 hours. The degree of expansion can be quantified by measuring and comparing the radius of the colony, R0 and R48.Back to article page