Table 3 Identification of top beta-value scored DNA methylated genes across stages
From: Systems biology approach to stage-wise characterization of epigenetic genes in lung adenocarcinoma
Stage | Hyper/Hypo | Genes in descending order of beta-values (p <0.001) |
|---|---|---|
I | Hyper | TLX3 > NEFM > PTGDR > AJAP1 > SIX6 > HOXA9 > TMEM130 > HISTIH3G > ATP8A2 > NID2 |
|  | Hypo | MMP26 > KRTAP 8–1 > REG3A > CORO6 > LY96 |
II | Hyper | LY96 > C10orf81 > KRTAP8-1 > MMP26 > REG3A > DEFB 119 > NMUR2 > MAGEB6 > IGKV7-3 < KRTAP15-1 |
|  | Hypo | HTR2C > GRIK3 > CNTP2 > SPHKAP > TMEM132D > NEFH > LEP > ZNF177 > HOXD10 > NKX 6-2 |
III | Hyper | TLX3 > HOXB4 > AJAP1 > HOXA4 > HOXD9 > PTGDR > LYPD5 > FZD10 > HOXD12 > NECAB2 |
|  | Hypo | CHR6 > C13orf28 > TMEM156 > XDH > FGF6 > IVL > G6PC > KRTAP8-1 > C10orf39 > FCRL3 |