From: Systems biology approach to stage-wise characterization of epigenetic genes in lung adenocarcinoma
DNA methylated genes | Stages | ||
---|---|---|---|
I | II | III | |
Common DNA methylated genes | |||
AJAP1 | √ | √ | √ |
FOXG1 | √ | √ | √ |
GRIK3 |  | √ | √ |
HAND2 |  |  | √ |
HOXD4 | √ | √ | √ |
PHOX2A | √ |  |  |
PRKCB | √ | √ | √ |
TLX3 |  | √ |  |
DNA methylated genes common with Stage I & II | |||
LY96 | √ | √ |  |
MSC |  | √ |  |
Hypermethylated genes common with Stage I & III | |||
GAS7 | √ |  | √ |
GRIK3 | √ |  |  |
HLA-G |  |  | √ |
HOXA9 |  |  | √ |
HOXD8 | Â | Â | Â |
HOXD12 |  |  | √ |
NID2 | Â | Â | Â |
TLX3 |  |  | √ |
DNA methylated genes common with Stage II & III | |||
SERPINB5 |  | √ | √ |
TAL1 |  |  | √ |
Top scored DNA methylated gene | |||
IVL |  |  | √ |
NEFM | √ |  |  |
TLX3 | √ |  | √ |