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Table 4 NADH balance

From: A metabolite-centric view on flux distributions in genome-scale metabolic models

Producing fluxes
Reaction/Enzyme Pathway/Product Ratio
glyceraldehyde-3-phosphate dehydrogenase glycolysis 52.74%
pyruvate dehydrogenase glycolysis/TCA cycle 32.14%
malate dehydrogenase TCA cycle 5.35%
phosphoglycerate dehydrogenase Ser 4.31%
2-oxoglutarate dehydrogenase TCA cycle 2.78%
3-isopropylmalate dehydrogenase Leu 1.11%
IMP dehydrogenase purines 0.60%
histidinol dehydrogenase His 0.47%
prephenate dehydrogenase Tyr 0.34%
glycine cleavage system folate metabolism 0.14%
Consuming fluxes
Reaction/Enzyme Pathway/Product Ratio
NADH dehydrogenase oxidative phosphorylation 94.48%
enoyl-[acyl-carrier-protein] reductase (11 reactions) fatty acids 5.10%
methylenetetrahydrofolate reductase Met 0.40%
  1. Total flux: 33.7 mmol gDW−1 h−1. Ratios below 0.05% not shown.
  2. Abbreviations: His, Leu, … – biosynthesis of L-amino acids.