Table 7 Split ratios of L-glutamate
From: A metabolite-centric view on flux distributions in genome-scale metabolic models
Producing fluxes | ||
|---|---|---|
Reaction/Enzyme | Pathway/Product | Ratio |
glutamate dehydrogenase | TCA cycle | 85.02% |
amidophosphoribosyltransferase | purines | 4.40% |
phosphoribosylformylglycinamidine synthase | purines | 4.40% |
GMP synthase | purines | 2.39% |
CTP synthase | CTP | 1.57% |
imidazole-glycerol-3-phosphate synthase | His, purines | 0.93% |
glutamine-fructose-6-phosphate transaminase | peptidoglycans, lipopolysaccharides | 0.72% |
anthranilate synthase | Trp | 0.56% |
Consuming fluxes | ||
Reaction/Enzyme | Pathway/Product | Ratio |
aspartate transaminase | Asp | 28.82% |
glutamine synthetase | Gln | 17.57% |
phosphoserine transaminase | Ser | 17.15% |
L-alanine transaminase | Ala | 5.55% |
leucine transaminase | Leu | 4.43% |
valine transaminase | Val | 4.16% |
succinyldiaminopimelate transaminase | Lys, peptidoglycans | 3.65% |
N-acetylglutamate synthase | Arg, polyamines | 3.31% |
acetylornithine transaminase | Arg, polyamines | 3.31% |
isoleucine transaminase | Ile | 2.85% |
Biomass | Â | 2.59% |
glutamate 5-kinase | Pro | 2.17% |
phenylalanine transaminase | Phe | 1.82% |
tyrosine transaminase | Tyr | 1.36% |
histidinol-phosphate transaminase | His | 0.93% |
glutamate racemase | peptidoglycans | 0.28% |
glutamyl-tRNA synthetase | cobalamin, heme | 0.05% |