Mapping condition-dependent regulation of metabolism in yeast through genome-scale modeling

BMC Systems Biology

Table 1 Summary of the characteristics of different yeast genome-scale metabolic models

	iFF708	iIN800	iMM904	Consensus	Yeast5	iTO977 (Current model)
Metabolites	825	985	1228	1168	1768	1353
-Unique metabolites	595	683	713	664	779	815
-Cytosolic metabolites	518	645	634	590	579	738
-Mitochondrial mets	170	209	241	235	308	231
-Peroxisomal mets	0	0	80	80	75	87
-Extracellular metabolites	137	131	164	158	168	156
Reactions	1145	1706	1577	1761	2034	1566
-Unique reactions	780	1041	1053	804	1068	1207
-Cytosolic reactions	723	1301	710	835	1092	1083
-Mitochondrial reactions	104	242	306	330	334	256
-Peroxisomal reactions	0	0	109	121	111	80
Genes	708	800	904	888	898	977
-Percentage¹	10.7%	12.1%	13.7%	13.4%	13.6%	14.8%
-Cytosolic genes	532	639	736	676	681	800
-Mitochondrial genes	104	124	199	190	204	212
-Peroxisomal genes	0	0	19	24	23	22

¹ Part of the genome that is included in the model. Based on the updated statistics from Saccharomyces Genome Database that includes 6607 genes. (as of Aug 29, 2010).

ISSN: 1752-0509