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Table 4 Parameters for FOXO mediated transcription

From: Computational modelling of the regulation of Insulin signalling by oxidative stress

Protein

FOXO- simulated transcription ktransl

Basal transcription kbasalt

RNA export kexp

RNA degradation kmdeg

RNA translation ktransl

Protein degradation kpdeg

Ref

InR

0.24

5.0

0.22

5.622

2.46

4.4× 10-3

[52, 53]

SOD2

0.95

15.0

0.22

5.622

1.23

1.9 × 10-3

[52][44, 54]

  1. Parameters for transcription, transport, translation and degradation of the FOXO-regulated InR and SOD2 genes and proteins.