Figure 2
From: A novel function prediction approach using protein overlap networks
Main sub-graph of yeast PON. (A) Main sub-graph consisting of two modules. (B) Network connections between two modules. The dashed line represents the edge between two nodes and the arrow indicates the domain connection within a protein. Two modules in the graph are connected by domain RWD [Pfam: PF05773] associated with protein binding function. Pkinase [Pfam: PF0069, upper module], DEAD [Pfam: PF00270, lower module], and Helicase_C [Pfam: PF00271, lower module] are prevailing domains associated with ATP binding function. Only annotated domains in InterPro database were presented for proteins GCN2 [UniProt: P15442], GIR2 [UniProt: Q03768], IMPACT homolog [UniProt: P25637], and a putative ATP-dependent RNA helicase [UniProt: Q06698].