Figure 4

Estimates for the primary model parameters for all experimental groups. J_TCA and P_dil denote the overall TCA cycle flux and the dilution fraction of labeled acetate entering the TCA cycle due to unlabeled endogenous substrates such as glucose and fatty acids, respectively. Estimates were first averaged for each heart and then all hearts were averaged for each group. The error bars represent the standard error of the mean (SEM) of the estimates of all hearts in one experimental group.