Global insights into energetic and metabolic networks in Rhodobacter sphaeroides

BMC Systems Biology

Table 1 Substrate utilization profile of R. sphaeroides under different growth conditions

Nutrient source	Previously known*	Predicted by iRsp1095**	Based on PM assay^a
			Photo	Aero	Anaerobic^b
Carbon	27	64	61 (190)	68 (190)	16 (41)
Nitrogen	3	31	66 (95)
Phosphorus	1	6	42 (59)
Sulfur	4	4	18 (35)
Total	35	105	187 (379)

*Previously known growth substrates under photosynthetic conditions.
**Includes 28 false positive predictions and predictions for 20 substrates not included on the various Biolog plates. The simulations for substrate utilization in iRsp1095 were done under aerobic and photosynthetic conditions.
^aThe values in parenthesis represent the total number of carbon, nitrogen, phosphorus or sulfur sources tested using PM and related approaches.
^bPhoto – photosynthetic growth; Aero – aerobic respiratory growth; Anaerobic – anaerobic respiratory growth using DMSO as the terminal electron acceptor.

ISSN: 1752-0509