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Figure 3 | BMC Systems Biology

Figure 3

From: Noise propagation through extracellular signaling leads to fluctuations in gene expression

Figure 3

Spatial distribution of the number of IFN-β surrounding dendritic cells. Displayed are the distributions at (A) 6 hours (B) 9 hours and (C) 11 hours post-infection. The colors indicate the range of the number of cytokines in each box surrounding a DC: black denotes an IFN-β protein number less than 133, green a number between 133 and 400, orange a number between 400 and 1200, and red a number greater than 1200. More than 80% have fewer than 133 at 6 hours while 97% have more than 1200 cytokines at 11 hours showing the emergence of spatial homogenization. The X- and Y-axes are in units of single cell length (~30 μm) as in Figure 2.

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