The fourth module identified by iMCMC in the GBM data and locations of the detected genes in known pathways. (A) Mutual exclusivity between any pair of genes is greater than 0.80 in this module. Thick gray line denotes a value more than 0.90 and thin line represents a value between 0.80 and 0.90. (B) The detected genes EGFR and NF1 are in the RTK signaling pathway, where the interactions are as reported in . The dense dashed line represents pair of genes with exclusivity more than 0.90 and correlation larger than 0.20. The loosely dashed line represents exclusivity more than 0.90 only, and the dot-and-dash curve represents correlation larger than 0.20 only.