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Table 5 Comparison of the functional enrichment of protein complexes identified by LF-PIN and other algorithms (for E.coli)

From: Identifying protein complexes based on density and modularity in protein-protein interaction network

Algorithms

[E-10,E-5]

[E-5, 0.01]

≥0.01 insignificant

<0.01 significant

LF-PIN

11(7.6%)

23(16.0%)

110(76.4%)

34(23.6%)

CMC

13(2.9%)

46(10.2%)

391(86.9%)

59(13.1%)

CPM

4(6.3%)

6(9.5%)

53(84.1%)

10(15.9%)

DPClus

11(7.6%)

51(10.8%)

410(87.0%)

61(13.0%)

HC-PIN

6(2.1%)

12(8.3%)

122(84.1%)

23(15.9%)

MCL

7(1.2%)

51(8.9%)

515(89.9%)

58(10.1%)

NFC

10(2.1%)

41(14.3%)

240(83.6%)

47(16.4%)

  1. The table lists the percentages of protein complexes identified by LF-PIN, CMC, CPM, DPClus, HC-PIN, MCL and NFC in PPI network of E.coli whose P-value falls within [E-10, E-5], [E-5, 0.01] and ≥0.01.