mRNA degradation dynamics of gene RPL30 construct ACT1 in single cells. (A, C) three simulations of X and L values over t for the detailed multi-step reaction model. (B, D) three simulations of X and L values over t for the two-variable model. For the detailed multi-step model, rate constants are s1 = 0, s2 = . . . = s10 = 0.112, and initial molecular numbers are ([A], [B], [BC 1], . . . , [BC 7]) = [4, 3, 3, 5, 15, 20, 20, 15, 15]. For the two-variable model, rate constant is k = 0.112, initial conditions (X0, L0) = (100, 371).