Figure 1
From: An approach for dynamical network reconstruction of simple network motifs
Network motifs. The 8 kinds of network motifs. The nodes shown as X1 to X4 represent regulator or regulon. RI, RM, and TM were modified by network motifs proposed by Herrgård et al. The structures of RI, RM, and TM were constructed according to the same network motif proposed by Herrgård et al. The structures of RI, RM, and TM were constructed according to the same concept of network motif proposed by Shen-Orr et al. The structures of AR and ML were constructed according to the same concept of network motif proposed by Lee al. (A) Regulatory Interaction (RI): a factor X1 regulates X2, X2 regulates X3, and X3 regulates X4. (B) Regulator Module (RM): a factor X1 regulates a set of regulons shown as X2 to X4. (C) Target Module (TM): a regulon X4 is regulated by other factors shown as X1 to X4. (D) Feed-Forward (FF): a regulator X1 regulates X2, and both jointly regulates X4. (E) Single Input Module (SIM): same as RM, a factor X 1 regulates a set of regulons shown as X2 to X4, and also regulates X1 itself. (F) Dense Overlapping Regulation(AR): regulons X3 and X4 were regulated by regulator X1 and X2, respectively. (G) Autoregulation: X1 regulates X2, X2 regulates X3, X3 regulates X4, and X4 inhibitory regulates X1. (F) Multicomponent-Loop (ML): X1 regulates X2, X2 inhibitory regulates X3, X3 regulates X4, and X4 inhibitory regulates X1.