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Table 4 The top 10 most upregulated genes following transfection and expression of Rnf14 variant 3 and variant 1 transcripts in C2C12 cells

From: RNF14 is a regulator of mitochondrial and immune function in muscle

Rnf14 variant 3 versus controls Gene ontology Fold change (Log2)
Ifit3 Interferon induced protein 2.22
G1p2 Interferon induced protein 2.20
2510004L01Rik (RSAD2) Interferon inducible 2.09
Oasl2 2'-5'-oligoadenylate synthetase activity 1.97
2310061N23Rik (Ifi27l2a) Interferon inducible 1.96
Ccl5 Chemokine ligand 5 1.91
AI481100 (Irgm2) Interferon induced GTPase 1.84
Usp18 A member of the deubiquitinating protease family of enzymes 1.76
Rnf14 This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression 1.75
Gbp4 Induced by interferon and hydrolyzes GTP 1.73
Rnf14 variant 1 versus controls Gene ontology  
Plac8 Placenta-specific, little known 2.07
G1p2 Interferon induced protein 1.99
Oasl2 2'-5'-oligoadenylate synthetase activity 1.82
Ccl5 Chemokine ligand 5 1.68
LOC223672 (Apol9a) Apolipoprotein, little known 1.65
2510004L01Rik Interferon inducible 1.61
2310016F22Rik (Apol9b) Apolipoprotein, little known 1.54
ifit3 Interferon induced protein 1.42
Gbp4 Guanylate-binding proteins induced by interferon 1.30
Oasl1 2'-5'-oligoadenylate synthetase activity 1.21
  1. Genes may be represented by more than one probe. The controls are a combination of untransfected cells and cells transfected with an empty construct.