Figure 5

The steady state solutions with the premature stop codon. This figure shows the effect of propensity of readthrough (μ) at the premature stop codon and the corresponding a) translation rate; b) codon density; and c) average occupancy of the mRNA, all at the steady state. Both the parallel (TASEP simulations) and random-sequential update rules (PBN model and TASEP simulations) are considered. The parameters are set as α=1,β=0.1, ${\gamma }_i=1,i\in {\mathbb{I}}_e$. The premature stop codon is at codon 25.