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Figure 5 | BMC Systems Biology

Figure 5

From: mRNA translation and protein synthesis: an analysis of different modelling methodologies and a new PBN based approach

Figure 5

The steady state solutions with the premature stop codon. This figure shows the effect of propensity of readthrough (μ) at the premature stop codon and the corresponding a) translation rate; b) codon density; and c) average occupancy of the mRNA, all at the steady state. Both the parallel (TASEP simulations) and random-sequential update rules (PBN model and TASEP simulations) are considered. The parameters are set as α=1,β=0.1, γ i =1,i I e . The premature stop codon is at codon 25.

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