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Table 1 Steady state concentrations obtained for optimized Model 2 with and without active transport

From: Analysis of Wnt signaling β-catenin spatial dynamics in HEK293T cells

Component

Steady state concentration (nM)

-

-

With active transport

Without active transport

Cytosol-membrane β-catenin

B 0 C

46.6

70.8

Cytosol-membrane Ligand

L 0 C

581.1

605.3

Cytosol-membrane complex

C 0 C

418.9

394.7

Nuclear β-catenin

B 0 N

32.6

61.8

Nuclear ligand

L 0 C

516.8

546.0

Nuclear complex

C 0 N

483.2

454.0