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Table 2 Metrics used to describe the tension transients and measured data for mouse at 37°C

From: Insight into model mechanisms through automatic parameter fitting: a new methodological framework for model development

Metric

Description

Land-model default output*

Experimental values

RT50

Time to 50% relaxation (ms)

24

16-30

RT90

Time to 90% relaxation (ms)

53

41-59

TTP

Time to peak tension (ms)

33

26-41

Peak

Peak tension (kPa)

41.1

32-52

Min

Minimum tension (kPa)

0.073

 
  1. These metrics were calculated from simulations using a Ca-transient.
  2. *From a simulation at resting sarcomere length.