Table 4 Autophagy-related proteins and association with dementia disease proteins
From: A systems biology investigation of neurodegenerative dementia reveals a pivotal role of autophagy
Disease | Disease protein | Disease protein | Mediator autophagy | Mediator autophagy |
|---|---|---|---|---|
Uniprot ID | Official gene symbol | Uniprot ID | Official gene symbol | |
AD | P02649 | APOE | P10636 | MAPT |
AD | P05067 | APP | P00519 | ABL1 |
AD | P05067 | APP | P49768 | PSEN1 |
AD | P05067 | APP | P10636 | MAPT |
AD | P05067 | APP | P07339 | CTSD |
AD | Q13867 | BLMH | Q13131 | PRKAA1 |
AD | Q13867 | BLMH | Q9BXW4 | MAP1LC3C |
AD | P29474 | NOS3 | P31749 | AKT1 |
AD | P49810 | PSEN2 | P49768 | PSEN1 |
AD | Q92673 | SORL1 | Q9H1Y0 | ATG5 |
AD | Q92673 | SORL1 | Q9C0C7 | AMBRA1 |
AD | Q92673 | SORL1 | Q13131 | PRKAA1 |
FTD | Q13148 | TARDBP | Q6ZNE5 | ATG14/KIAA0831 |
FTD | Q13148 | TARDBP | O95166 | GABARAP |
FTD | Q13148 | TARDBP | P54646 | PRKAA2 |
FTD | Q13148 | TARDBP | Q13286 | CLN3 |
FTD | Q13148 | TARDBP | Q5MNZ9 | WIPI1 |
FTD | Q13148 | TARDBP | Q676U5 | ATG16L1 |
FTD | Q13148 | TARDBP | Q9BSB4 | C12orf44/ATG101 |
FTD | Q13148 | TARDBP | Q9H1Y0 | ATG5 |
FTD | Q13148 | TARDBP | Q9Y484 | WDR45 |
FTD | Q13148 | TARDBP | Q9Y4P8 | WIPI2 |
FTD | P49768 | PSEN1 | P10415 | BCL2 |
FTD | P49768 | PSEN1 | Q07817 | BCL2L1 |
FTD/PSNP | P10636 | MAPT | O60260 | PARK2 |
FTD/PSNP | P10636 | MAPT | P00519 | ABL1 |
FTD/PSNP | P10636 | MAPT | P31749 | AKT1 |
FTD/PSNP | P10636 | MAPT | P49768 | PSEN1 |
FTD/PSNP | P10636 | MAPT | Q13501 | SQSTM1 |
ALSPD | Q99497 | PARK7 | Q6ZNE5 | ATG14/ KIAA0831 |
ALSPD | Q99497 | PARK7 | Q9Y484 | WDR45 |
ALSPD | Q99497 | PARK7 | Q13286 | CLN3 |
ALSPD | Q99497 | PARK7 | Q9H1Y0 | ATG5 |
ALSPD | Q99497 | PARK7 | Q9Y4P8 | WIPI2 |
ALSPD | Q99497 | PARK7 | Q15831 | STK11 |
ALSPD | Q99497 | PARK7 | Q9P2Y5 | UVRAG |
ALSPD | Q99497 | PARK7 | Q7Z6L1 | TECPR1 |
LBD | P37840 | SNCA | Q9H0R8 | GABARAPL1,3/ATG8 |
LBD | P37840 | SNCA | Q92934 | BAD |