Skip to main content

Table 11 Distribution of essential, drug target and classical cancer proteins in CN zones

From: Modelling human protein interaction networks as metric spaces has potential in disease research and drug target discovery

Zone

Essential

Disease

Drug

Oncogenes

Tumour

 

genes

associated

targets

 

suppressors

1

206 (38%)

234 (43.2%)

97 (17.8%)

17 (3.1%)

20 (3.6%)

2

1084 (18%)

1279 (21.3%)

365 (6%)

32 (0.5%)

42 (0.6%)

3

315 (9.3%)

415 (12.4%)

59 (1.7%)

2 (0.05%)

4 (0.1%)

4

28 (7.6%)

56 (15.3%)

3 (0.8%)

1 (0.2%)

1 (0.2%)

5

2 (3.2%)

9 (14.8%)

1 (1.6%)

-

-