Cellular | # of proteins | Zone 1 | Zone 2 | Zone 3 |
---|---|---|---|---|
function | Â | Â | Â | Â |
Signalling pathway | 3186 | 285 (76.2%) | 2141 (46.4%) | 760 (20.8%) |
Positive signals | 544 | 75 (20%) | 386 (8.3%) | 83 (2.2%) |
Negative signals | 449 | 57 (15.2%) | 321 (6.9%) | 71 (1.9%) |
MAPK signalling cascade | 394 | 93 (24.8%) | 258 (5.5%) | 43 (1.1%) |
Apoptosis signalling pathway | 38 | 13 (3.4%) | 19 (0.4%) | 6 (0.1%) |
Positive regulation of apoptosis signalling | 22 | 6 (1.6%) | 13 (0.2%) | 3 (0.1%) |
Negative regulation of apoptosis signalling | 10 | 4 (1%) | 3 (0.06%) | 3 (0.08%) |