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Table 7 HFPIN zone distribution of proteins consistently expressed in cancer samples

From: Modelling human protein interaction networks as metric spaces has potential in disease research and drug target discovery

Type of cancer # proteins Zone 1 Zone 2 Zone 3 Zone 4 Zone 5 Zone 6
Breast 330 11 (3.3%) 189 (57.2%) 121 (36.6%) 9 (2.7%) - -
Cervical 711 26 (3.6%) 425 (59.7%) 230 (32.3%) 23 (3.2%) 7 (0.9%) -
Endometrial 1515 57 (3.7%) 839 (55.3%) 514 (33.9%) 83 (5.4%) 20 (1.3%) 2 (0.1%)
Fallopian 1292 49 (3.7%) 715 (55.3%) 446 (34.5%) 67 (5.1%) 14 (1%) 1 (0.07%)
Glioblastoma 1046 38 (3.6%) 589 (56.3%) 368 (35.1%) 44 (4.2%) 6 (0.5%) 1 (0.9%)
Glioma 1180 40 (3.3%) 621 (57.7%) 440 (37.2%) 63 (5.3%) 13 (1.1%) 3 (0.2%)
Kidney 561 14 (2.4%) 331 (59%) 193 (34.4%) 23 (4%) - -
Liver 715 29 (4%) 402 (56.2%) 247 (34.5%) 33 (4.6%) 4 (0.5%) -
Lung 532 19 (3.5%) 314 (59%) 175 (32.8%) 22 (4.1%) 2 (0.3%) -
Ovarian 775 26 (3.3%) 432 (55.7%) 279 (36%) 32 (4.1%) 6 (0.7%) -
Pancreatic 717 30 (4.1%) 411 (57.3%) 244 (34%) 28 (3.9%) 4 (0.5%) -
Pituitary 1126 37 (3.2%) 591 (52.4%) 421 (37.3%) 61 (5.4%) 15 (1.3%) 1 (0.08%)
Rectal 1597 69 (4.3%) 861 (53.9%) 552 (34.5%) 90 (5.6%) 23 (1.4%) 2 (0.1%)
Average   3.5% 56.5% 34.8% 4.4% 0.7% 0.1%