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Table 7 HFPIN zone distribution of proteins consistently expressed in cancer samples

From: Modelling human protein interaction networks as metric spaces has potential in disease research and drug target discovery

Type of cancer

# proteins

Zone 1

Zone 2

Zone 3

Zone 4

Zone 5

Zone 6

Breast

330

11 (3.3%)

189 (57.2%)

121 (36.6%)

9 (2.7%)

-

-

Cervical

711

26 (3.6%)

425 (59.7%)

230 (32.3%)

23 (3.2%)

7 (0.9%)

-

Endometrial

1515

57 (3.7%)

839 (55.3%)

514 (33.9%)

83 (5.4%)

20 (1.3%)

2 (0.1%)

Fallopian

1292

49 (3.7%)

715 (55.3%)

446 (34.5%)

67 (5.1%)

14 (1%)

1 (0.07%)

Glioblastoma

1046

38 (3.6%)

589 (56.3%)

368 (35.1%)

44 (4.2%)

6 (0.5%)

1 (0.9%)

Glioma

1180

40 (3.3%)

621 (57.7%)

440 (37.2%)

63 (5.3%)

13 (1.1%)

3 (0.2%)

Kidney

561

14 (2.4%)

331 (59%)

193 (34.4%)

23 (4%)

-

-

Liver

715

29 (4%)

402 (56.2%)

247 (34.5%)

33 (4.6%)

4 (0.5%)

-

Lung

532

19 (3.5%)

314 (59%)

175 (32.8%)

22 (4.1%)

2 (0.3%)

-

Ovarian

775

26 (3.3%)

432 (55.7%)

279 (36%)

32 (4.1%)

6 (0.7%)

-

Pancreatic

717

30 (4.1%)

411 (57.3%)

244 (34%)

28 (3.9%)

4 (0.5%)

-

Pituitary

1126

37 (3.2%)

591 (52.4%)

421 (37.3%)

61 (5.4%)

15 (1.3%)

1 (0.08%)

Rectal

1597

69 (4.3%)

861 (53.9%)

552 (34.5%)

90 (5.6%)

23 (1.4%)

2 (0.1%)

Average

 

3.5%

56.5%

34.8%

4.4%

0.7%

0.1%