Figure 1

Groups and outliers detection by 2D PCA scatterplot in plasma samples. The 2D scatterplot uses the first two PCs to display the relationship between plasma samples (dots) as indicated by inter-individual distances. See ‘Methods’ section for the interpretation of samples and between-samples positions. Briefly, points that cluster together correspond to samples behaving similarly. Notice how samples form groups by experimental conditions and the absence of outliers. WT-LF, WT-HF, MU-LF, and MU-HF stand for the following groups: Apc Wild-Type - Low Fat Diet, Apc Wild-Type - High Fat Diet, Apc Mutant - Low Fat Diet, Apc Mutant - High Fat Diet respectively.