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Table 3 List of annotated plasma metabolites having a significant correlation with polyp counts in association with a Genotype by Diet interaction effect

From: Metabolomics of Apc Min/+ mice genetically susceptible to intestinal cancer

Metabolite

HMDB

CAS

KEGG

p.val

Adj.p.val

Uracil

HMDB00300

66-22-8

C00106

2.555E-11

2.130E-10

Palmetoleic acid

HMDB03229

373-49-9

C08362

2.311E-02

3.533E-02

Serine

HMDB00187

56-45-1

C00065

5.215E-02

3.533E-02

Glycine 2TMS

HMDB00123

56-40-6

C00037

9.164E-02

3.533E-02

Glucose

HMDB00122

50-99-7

C00031

1.203E-01

3.533E-02

Methionine

HMDB00696

63-68-3

C00073

1.339E-01

3.533E-02

Palmitate

HMDB00220

57-10-3

C00249

1.419E-01

3.533E-02

Gluconic acid

HMDB00625

526-95-4

C00257

1.432E-01

3.533E-02

Stearic acid

HMDB00827

57-11-4

C01530

1.457E-01

3.533E-02

Tryptophane

HMDB00929

73-22-3

C02983

1.481E-01

3.533E-02

Glycerol-1-phosphate

HMDB00126

57-03-4

C00093

1.507E-01

3.533E-02

Erytrithol

 

149-32-6

 

1.595E-01

3.533E-02

Threonine

HMDB00167

72-19-5

C00188

1.735E-01

3.533E-02

Fumarate

HMDB00134

110-17-8

C00122

1.744E-01

3.533E-02

Hippuric acid

HMDB00714

495-69-2

C01586

1.786E-01

3.533E-02

1-Monopalmitin

   

1.829E-01

3.533E-02

Cholesterol

HMDB00067

57-88-5

C00249

1.924E-01

3.533E-02

Phenylalanine

HMDB00159

63-91-2

C00079

2.023E-01

3.533E-02

Glutamic acid

HMDB00134

110-17-8

C00122

2.046E-01

3.533E-02

Lysine

HMDB00182

56-87-1

C00047

2.158E-01

3.533E-02

Proline

HMDB00162

147-85-3

C00148

2.290E-01

3.533E-02

Creatinine

HMDB00562

60-27-5

C00791

2.331E-01

3.533E-02

Succinic acid

HMDB00254

110-15-6

C00042

2.355E-01

3.533E-02

2-Monopalmitin

 

19670-51-0

 

2.428E-01

3.533E-02

1,2 Dipalmitin

 

761-35-3

 

2.600E-01

3.533E-02

Norleucine

HMDB01645

327-57-1

C01933

2.633E-01

3.533E-02

Ascorbic acid

HMDB00044

50-81-7

C00072

2.716E-01

3.533E-02

Urea

HMDB00294

57-13-6

C00086

2.756E-01

3.533E-02

Nicotinamide

HMDB01406

98-92-0

C00153

2.932E-01

3.584E-02

Pyrophosphate

HMDB00250

14000-31-8

C00013

2.992E-01

3.584E-02

Alanine

HMDB00161

56-41-7

C00041

3.127E-01

3.670E-02

Ribose-5-phosphate

HMDB01548

3615-55-2

C00117

3.287E-01

3.756E-02

1,3-Dipalmitin

HMDB31011

502-52-3

 

3.372E-01

3.763E-02

2-Amino adipic acid

HMDB00510

542-32-5

C00956

3.440E-01

3.763E-02

Pyroglutamic acid

HMDB00267

98-79-3

C01879

3.553E-01

3.763E-02

Glutamine

HMDB00641

56-85-9

C00064

3.568E-01

3.763E-02

Pyruvate

HMDB00243

127-17-3

C00022

3.569E-01

3.763E-02

Valine

HMDB00883

72-18-4

C00183

3.790E-01

3.769E-02

Inositol phosphate

HMDB34220

551-72-4

C06151

3.879E-01

3.769E-02

Malic acid

HMDB00744

6915-15-7

C00711

4.790E-01

4.158E-02

Glycerol

HMDB00131

56-81-5

C00116

5.514E-01

4.642E-02

Glycine

HMDB00123

56-40-6

C00037

5.824E-01

4.805E-02

  1. Raw p-values from the Generalized Linear Model are reported with pFDR-adjusted p-values as described in the ‘Methods’ section. Metabolites with pFDR ≤ 0.05 are shown and ranked by pFDR-adjusted or equivalently by raw p-values. Accession numbers from the Human Metabolome Database accession (HMDB), the Kyoto Encyclopedia of Genes and Genomes (KEGG) databases, and Chemical Abstract Service (CAS) are provided. Only annotated compounds of the list of significant compounds are shown here. The full list with hyperlinked accession numbers is provided in (Additional file 9: Table S5).
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BMC Systems Biology

ISSN: 1752-0509

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