Table 1 Correlations between selectivity and kinase activity from primary and secondary screening
Kinase | Selectivity corr | FDR | Kinase | Selectivity corr | FDR |
|---|---|---|---|---|---|
Primary screening | Secondary screening | ||||
PRKCZ | 0.451 | 2.28E-08 | TGFBR2 | -0.501 | 8.29E-08 |
DMPK | 0.435 | 7.75E-08 | CDK4 | -0.412 | 6.40E-05 |
STK39 | 0.430 | 1.15E-07 | CDC42BPB | -0.409 | 6.40E-05 |
EPHA8 | 0.420 | 2.33E-07 | RIPK2 | -0.399 | 7.73E-05 |
ADRBK2 | 0.399 | 1.01E-06 | DSTYK | -0.369 | 0.000413 |
PRKACG | 0.396 | 1.27E-06 | ACVRL1 | -0.368 | 0.000413 |
CAMK4 | 0.394 | 1.45E-06 | PAK1 | -0.367 | 0.000413 |
MAP2K2 | 0.393 | 1.53E-06 | MAPKAPK2 | -0.364 | 0.000413 |
ADRBK1 | 0.392 | 1.62E-06 | PAK7 | -0.359 | 0.000424 |
PNCK | 0.382 | 3.29E-06 | CDK1 | -0.357 | 0.000429 |