Figure 3

Reconstructed short-term signalling networks. The figure displays the reconstructed short-term signalling networks coloured according to the preserved prior reference network (black) and newly inferred (added) individual edges per cell line. Target proteins are represented as rectangles with stimuli and drugs coloured in red. The three drug names erlotinib, trastuzumab and pertuzumab are abbreviated via their first letters. Solid arrows denote activating interactions while dashed ones represent inhibitions.