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Figure 6 | BMC Systems Biology

Figure 6

From: Systems biology modeling of omics data: effect of cyclosporine a on the Nrf2 pathway in human renal cells

Figure 6

Model predictions of the time course of ROS and Nrf2 protein after repeated CsA exposures. Cytosolic ROS quantity after 5 μM 14 days repeated CsA exposure (A1), 15 μM CsA (A2) and nuclear Nrf2 quantity after 5 μM CsA exposure (B1) and 15 μM CsA (B2). The blue line indicates the best fitting (maximum posterior probability) model prediction. The black lines (normal scales) and red lines (semi-logarithmic scales) are predictions made with 49 random posterior parameter sets.

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