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Table 5 t-tests of microarray measurements between genotype and DNA methylation for blood, normal and tumor tissues.

From: Genes associated with genotype-specific DNA methylation in squamous cell carcinoma as candidate drug targets

Nsp

 

Genotype

DNA methylation

P- value

blood

1.32

1.19

3.1 × 10− 12

normal tissue

2.45

1.75

∗

tumor

2.84

2.23

∗

Sty1

 

Genotype

DNA methylation

P- value

blood

2.21

1.77

∗

normal tissue

2.58

2.14

∗

tumor

2.87

2.48

∗

Sty2

 

Genotype

DNA methylation

P- value

blood

1.69

1.29

∗

normal tissue

2.42

2.02

∗

tumor

2.51

2.04

∗

  1. Nsp and Sty are the microarray data sets used in the study. Sty1 and Sty2 correspond to the PC4 for genotype (Figures 4d and 6b)/PC3 for DNA methylation (Figures 5c and 6c) and PC3 for genotype (Figures 4c and 6a)/PC4 for DNA methylation (Figures 5d and 6d) combinations of PCs. ∗ indicates P-values < 2.2 x 10−16.
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BMC Systems Biology

ISSN: 1752-0509

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