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Table 4 Results on Independent dataset PDB186 of different predictorsa

From: Identifying DNA-binding proteins by combining support vector machine and PSSM distance transformation

Methods Acc(%) MCC Sn(%) Sp(%) AUC(%)
iDNA-Prot 67.20 0.344 67.70 66.70 83.30
DNA-Prot 61.80 0.240 69.90 53.80 79.60
DNAbinder 60.80 0.216 57.00 64.50 60.70
DNABIND 67.70 0.355 66.70 68.80 69.40
DNA-Threader 59.70 0.279 23.70 95.70 N/A
DBPPred 76.90 0.538 79.60 74.20 79.10
PSSM-DT 80.00 0.647 87.09 72.83 87.40
  1. The six methods in the front of the table are six useful predicting methods for identification of DNA-binding proteins proposed in the past and were demonstrated to have good performance. The results of the six existing predicting methods and the SVM-PSSM-DT were achieved on the dataset PDB186 by their model trained on benchmark dataset.
  2. aThe results of iDNA-Prot [16], DNA-Prot [74], DNAbinder[21], DNABIND [34], DNA-Threader [78] and DDPPred [75] were obtained from [75].