Figure 3

Sensitivity analysis for the two-module network with the TetR/Ptet-based NOT gate, when OUTPUT ₁ is affected by constant CV noise: variability among the estimated parameters and maximum percentage difference between estimated and true parameters. CV among the estimated parameters (A,C), and maximum percentage difference between estimated and true parameters (B,D) for different values of k _OUT (A-B) and η _OUT (C-D). CV was computed among the parameters estimated for noise CV = 0.15, 0.55 and 0.75.