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Table 5 Estimated parameters for the three-module network considered as a black-box function, for different noise entities and constant CV noise model, when the function is simulated by using the three-module network of Figure 1H.

From: Modelling the effects of cell-to-cell variability on the output of interconnected gene networks in bacterial populations

Parameter: α OUT
[RPU]
δ OUT
[RPU]
k OUT
[RPU]
η OUT
[-]
constant CV 0.22
0.22
0.22
0.20
0.20
0.20
0.19
0.19
0.19
(6.5%)
0.28
0.28
0.28
0.30
0.30
0.30
0.31
0.31
0.31
16.90
20.78
24.42
18.90
23.10
25.91
19.32
23.71
27.97
(16.2%)
1.73
1.41
1.26
1.73
1.41
1.22
1.66
1.38
1.24
(14.3%)
  1. Parameters are obtained by fitting population-averaged values of OUTPUT2 as a function of OUTPUT1 for different noise models and entity, applied to OUTPUT1. The 9 values reported in each cell correspond to a noise (which affects OUTPUT1 and OUTPUT2, respectively) of CV = 0.15-0.15, 0.15-0.55, 0.15-0.75, 0.55-0.15, 0.55-0.55, 0.55-0.75, 0.75-0.15, 0.75-0.55, 0.75-0.75. The CV among the estimated parameters is reported in brackets.