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Table 1 Novel Plasmodium falciparum proteins that were predicted to be functional orthologs of pathogenesis-related proteins in E.coli

From: Predicting and exploring network components involved in pathogenesis in the malaria parasite via novel subnetwork alignments

PlasmoDB Accession Number Annotation Degree of Connectivity
PF3D7_1365900 60S ribosomal protein L40/UBI, putative 180
PF3D7_1241800 DEAD/DEAH box ATP-dependent RNA helicase, putative 98
PF3D7_0306800 T-complex protein beta subunit, putative 43
PF3D7_0823300 histone acetyltransferase GCN5 (GCN5) 20
PF3D7_1318700 conserved Plasmodium protein, unknown function 19
PF3D7_1212800 iron-sulfur subunit of succinate dehydrogenase 18
PF3D7_0208600 ribosome-recycling factor, putative (RRF) 16
PF3D7_1416900 prefoldin subunit 2, putative 15
PF3D7_0731100 Plasmodium exported protein (PHISTc), unknown function (GEXP11) 14
PF3D7_1013500 phosphoinositide-specific phospholipase C (PI-PLC) 11
PF3D7_0810600 RNA helicase, putative 9
PF3D7_1337200 1-deoxy-D-xylulose 5-phosphate synthase 7
PF3D7_1148800 Plasmodium exported protein (hyp11), unknown function 6
PF3D7_1008000 inositol polyphosphate kinase, putative (IPK1) 6
PF3D7_0919000 nucleosome assembly protein (NAPS) 6
PF3D7_1418000 ubiquitin fusion degradation protein UFD1, putative (UFD1) 5
PF3D7_0300100 erythrocyte membrane protein 1, PfEMP1 (VAR) 5
PF3D7_1342400 casein kinase II beta chain (CK2beta2) 1
PF3D7_1318700 conserved Plasmodium protein, unknown function 0
PF3D7_1364200 conserved Plasmodium protein, unknown function 0
PF3D7_1229300 conserved Plasmodium protein, unknown function 0
PF3D7_1451200 conserved Plasmodium protein, unknown function 0
PF3D7_0310900 conserved Plasmodium protein, unknown function 0
PF3D7_1008100 conserved Plasmodium protein, unknown function 0