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Table 4 The connections and perturbation stabilities of the 10 significant drugs obtained for the 148-gene signature.

From: Connectivity mapping using a combined gene signature from multiple colorectal cancer datasets identified candidate drugs including existing chemotherapies

Compound Replicate cscore pvalue zscore PerturbStability
trichostatin A 182 -0.144 5.0E-06 -5.87 1.00
vorinostat 12 -0.146 1.0E-05 -4.63 1.00
HC toxin 1 -0.217 5.0E-06 -4.57 1.00
sodium phenylbutyrate 7 -0.072 5.0E-06 -4.56 1.00
mycophenolic acid 3 -0.145 2.0E-05 -4.41 1.00
irinotecan 3 -0.146 1.0E-05 -4.18 1.00
etoposide 4 -0.087 3.9E-04 -3.34 0.90
valproic acid 57 -0.036 5.9E-04 -3.19 0.78
arachidonic acid 3 -0.094 5.8E-04 -3.18 0.77
rifabutin 3 -0.100 6.3E-04 -3.23 0.74