Table 4 The connections and perturbation stabilities of the 10 significant drugs obtained for the 148-gene signature.
Compound | Replicate | cscore | pvalue | zscore | PerturbStability |
|---|---|---|---|---|---|
trichostatin A | 182 | -0.144 | 5.0E-06 | -5.87 | 1.00 |
vorinostat | 12 | -0.146 | 1.0E-05 | -4.63 | 1.00 |
HC toxin | 1 | -0.217 | 5.0E-06 | -4.57 | 1.00 |
sodium phenylbutyrate | 7 | -0.072 | 5.0E-06 | -4.56 | 1.00 |
mycophenolic acid | 3 | -0.145 | 2.0E-05 | -4.41 | 1.00 |
irinotecan | 3 | -0.146 | 1.0E-05 | -4.18 | 1.00 |
etoposide | 4 | -0.087 | 3.9E-04 | -3.34 | 0.90 |
valproic acid | 57 | -0.036 | 5.9E-04 | -3.19 | 0.78 |
arachidonic acid | 3 | -0.094 | 5.8E-04 | -3.18 | 0.77 |
rifabutin | 3 | -0.100 | 6.3E-04 | -3.23 | 0.74 |