Figure 8
From: Disentangling the multigenic and pleiotropic nature of molecular function
Genetic interactions (GIs) within pathways and pathway clusters. GIs are classified depending on whether the genes are in the same pathway, within two pathways in the same network cluster, or uncharacterised (between two pathways in different clusters or involving unclustered pathways). Genes present in multiple pathways will result in GIs appearing in many pathway pairs. In these situations all pathway pairs are classified separately. The yellow nodes show three pathways in a single cluster. The green node represents a pathway in a separate cluster. All possible ways of connecting gene 1 and gene 2 across all pathways are explored.