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Figure 3 | BMC Systems Biology

Figure 3

From: Positive regulation of Rho GTPase activity by RhoGDIs as a result of their direct interaction with GAPs

Figure 3

Prolongation of Rho activation in the GDI-integrated model is dependent on K m GAP/GDI and the GAP concentration. Rho activation dynamics were simulated at various K mGEF/GDI values (A), K mGAP/GDI values (B), GEF concentration (C), and GAP concentrations (D) in the GDI-integrated model. The activation levels of GTPases were expressed as the concentration of GTP-Rho/Effector complex.

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BMC Systems Biology

ISSN: 1752-0509

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