From: BioPreDyn-bench: a suite of benchmark problems for dynamic modelling in systems biology
Model ID | B1 | B2 | B3 | B4 | B5 | B6 |
---|---|---|---|---|---|---|
p ^{U} | 5·p _{ nom } | \(10\cdot p_{\textit {nom}}^{(ex)}\) | \(10\cdot p_{\textit {nom}}^{(ex)}\) | 5·p _{ nom } | varying | varying |
p ^{L} | 0.2·p _{ nom } | \(0.1\cdot p_{\textit {nom}}^{(ex)}\) | \(0.1\cdot p_{\textit {nom}}^{(ex)}\) | 0.2·p _{ nom } | varying | varying |
Local method | DHC | FMINCON | none | FMINCON | DHC | FMINCON |
CPU time | ≈170 hours | ≈3 hours | ≈336 hours | ≈1 hour | ≈16 hours | ≈24 hours |
Evaluations | 6.9678·10^{5} | 9.0728·10^{4} | 7.2193·10^{6} | 1.6193·10^{5} | 8.8393·10^{4} | 2.0751·10^{6} |
J _{0} | 5.8819·10^{9} | 3.1136·10^{4} | 4.6930·10^{16} | 6.6034·10^{8} | 3.1485·10^{4} | 8.5769·10^{5} |
J _{ f } | 1.3753·10^{4} | 2.3390·10^{2} | 3.7029·10^{−1} | 4.5718·10^{1} | 3.0725·10^{3} | 1.0833·10^{5} |
J _{ nom } | 1.0846·10^{6} | − | 0 | 3.9068·10^{1} | 4.2737·10^{3} | − |
\(\sum \textit {NRMSE}_{0}\) | 3.5834·10^{1} | 8.5995·10^{−2} | 3.5457·10^{1} | 4.8005·10^{1} | 4.0434·10^{1} | 2.3808·10^{2} |
\(\sum \textit {NRMSE}_{f}\) | 5.7558 | 2.4921 | 2.9298·10^{−1} | 2.8010 | 2.7430·10^{1} | 1.6212·10^{2} |
\(\sum \textit {NRMSE}_{\textit {nom}}\) | 3.8203 | − | 0 | 2.8273 | 3.0114·10^{1} | − |