Figure 5

Inhibitor shock. A) Plot showing the addition of HMF and furfural in culture supernatants and the temporary disruption of growth. B) Plot showing the levels of intracellular citric acid and hydroxymethylfurfurol, as well as the average of all other metabolites. C) A heat map of a hierarchical clustering of the concentration of all monitored intracellular metabolites over the course of the 4 hour experiment.