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Fig. 1 | BMC Systems Biology

Fig. 1

From: Increased robustness of early embryogenesis through collective decision-making by key transcription factors

Fig. 1

Waddington landscape of the mouse preimplantation embryo. a The original artwork of Waddington (we have added the arrows and the labels). b Principal component analysis (PCA) of the mouse preimplantation embryo gene expression profiles. Each point represents one cell, and the color of each point shows the developmental stage of the cell. c Schematic representation of mouse preimplantation embryonic development. d The computational Waddington landscape of the mouse early development based on the gene expression profiles. Each ball represents a single cell. PC: Principal component, ICM: Inner cell mass, TE: Trophectoderm, PE: Primitive endoderm, EPI: Epiblast

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BMC Systems Biology

ISSN: 1752-0509

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