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Table 2 Stoichiometries of metabolites in the biomass synthesis reaction of the ColiCore and the ColiPrunedComp network model. Negative values indicate consumption, positive values production during biomass synthesis

From: An algorithm for the reduction of genome-scale metabolic network models to meaningful core models

Metabolite Coefficient in BSR of ColiCore [mmol] Coefficient in BSR of ColiPrunedComp [mmol]
2-Oxoglutarate 4.1182 7.4661
3-Phospho-D-glycerate −1.4960 −1.7175
Acetate   0.5810
Acetyl-CoA −3.7478 −3.8560
ADP 59.8100 67.7163
AMP   2.2653
ATP −59.8100 −69.9816
CO2   1.7341
Coenzyme-A 3.7487 4.3809
Dihydroxyacetone-phosphate   −0.1413
Erythrose-4-phosphate −0.3610 −0.3720
Formate   −0.1080
Fructose-6-phosphate −0.0709 −0.0945
Fumarate   0.7063
Glucose-6-phosphate −0.2050  
Glutamate −4.9414 −6.7339
Glutamine −0.2557 −1.8075
Glyceraldehyde-3-phosphate −0.1290 0.0540
Glyoxylate   0.0007
H_c 59.8100 64.5223
H_p   −0.1686
H2O −59.8100 −57.4196
NAD −3.5470 −0.3971
NADH 3.5470 0.3971
NADP 13.0279 7.2399
NADPH −13.0279 −7.2399
NH4   −0.4352
Oxaloacetate −1.7867 −2.9257
Phosphoenolpyruvate −0.5191 −0.8102
Pi_c 59.8100 75.3394
Pyruvate −2.8328 −2.7842
Ribose-5-phosphate −0.8977 −0.9325
Ribulose-5-phosphate   −0.0398
Succinate   0.8586
Succinyl-CoA   −0.5249
Several external metabolites including trace elements (calcium, sulfate, cobalt, copper, etc.)   (several amounts)