Table 2 Stoichiometries of metabolites in the biomass synthesis reaction of the ColiCore and the ColiPrunedComp network model. Negative values indicate consumption, positive values production during biomass synthesis
From: An algorithm for the reduction of genome-scale metabolic network models to meaningful core models
Metabolite | Coefficient in BSR of ColiCore [mmol] | Coefficient in BSR of ColiPrunedComp [mmol] |
|---|---|---|
2-Oxoglutarate | 4.1182 | 7.4661 |
3-Phospho-D-glycerate | −1.4960 | −1.7175 |
Acetate | Â | 0.5810 |
Acetyl-CoA | −3.7478 | −3.8560 |
ADP | 59.8100 | 67.7163 |
AMP | Â | 2.2653 |
ATP | −59.8100 | −69.9816 |
CO2 | Â | 1.7341 |
Coenzyme-A | 3.7487 | 4.3809 |
Dihydroxyacetone-phosphate |  | −0.1413 |
Erythrose-4-phosphate | −0.3610 | −0.3720 |
Formate |  | −0.1080 |
Fructose-6-phosphate | −0.0709 | −0.0945 |
Fumarate | Â | 0.7063 |
Glucose-6-phosphate | −0.2050 |  |
Glutamate | −4.9414 | −6.7339 |
Glutamine | −0.2557 | −1.8075 |
Glyceraldehyde-3-phosphate | −0.1290 | 0.0540 |
Glyoxylate | Â | 0.0007 |
H_c | 59.8100 | 64.5223 |
H_p |  | −0.1686 |
H2O | −59.8100 | −57.4196 |
NAD | −3.5470 | −0.3971 |
NADH | 3.5470 | 0.3971 |
NADP | 13.0279 | 7.2399 |
NADPH | −13.0279 | −7.2399 |
NH4 |  | −0.4352 |
Oxaloacetate | −1.7867 | −2.9257 |
Phosphoenolpyruvate | −0.5191 | −0.8102 |
Pi_c | 59.8100 | 75.3394 |
Pyruvate | −2.8328 | −2.7842 |
Ribose-5-phosphate | −0.8977 | −0.9325 |
Ribulose-5-phosphate |  | −0.0398 |
Succinate | Â | 0.8586 |
Succinyl-CoA |  | −0.5249 |
Several external metabolites including trace elements (calcium, sulfate, cobalt, copper, etc.) | Â | (several amounts) |