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Fig. 3 | BMC Systems Biology

Fig. 3

From: Constructing an integrated genetic and epigenetic cellular network for whole cellular mechanism using high-throughput next-generation sequencing data

Fig. 3

The integrated genetic and epigenetic cellular network for investigating the cellular mechanisms of normal and tumor tissues in gastric cancer. The associations include the networks in tumor cells (dotted lines), normal cells (dashed lines), and both (solid lines). The bold lines indicate large genetic and epigenetic regulatory effects or genetic expression. Dysregulation of MIR7 contributes to initiation and progression of inflammation-induced gastric cancer, and PML, a potential drug target, overcomes platinum resistance in platinum-based chemotherapy in gastric cancer

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BMC Systems Biology

ISSN: 1752-0509

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