Skip to main content

Table 2 Entities, networks and communities overlap comparisons

From: Comparing Alzheimer’s and Parkinson’s diseases networks using graph communities structure

A) Common entities

 
 

Alzheimer

    

Alzheimer

-

Parkinson

   

Parkinson

12 %

-

Influenza

  

Influenza

8 %

8 %

-

mTOR

 

mTOR

6 %

8 %

3 %

-

Random*

Random*

0.17 %

0.11 %

0.28 %

0.02 %

-

B) Common interactions

 
 

Alzheimer

    

Alzheimer

-

Parkinson

   

Parkinson

81 %

-

Influenza

  

Influenza

69 %

68 %

-

mTOR

 

mTOR

77 %

86 %

64 %

-

Random*

Random*

8.83 %

7.7 %

8.97 %

3.5 %

-

C) Similar communities

 
 

Alzheimer

    

Alzheimer

-

Parkinson

   

Parkinson

36 %

-

Influenza

  

Influenza

28 %

27 %

-

mTOR

 

mTOR

35 %

39 %

22 %

-

Random*

Random*

0.66 %

1.18 %

0.15 %

2.47 %

-

  1. A) shows the percentage of common entities among the four lists analyzed calculated with Jaccard distance. B) Shows the overlap in terms of links between the four induced networks analyzed calculated with Hamming similarity. C) shows results obtained counting overlapping community pairs that have a functional similarity that falls in the fifth quintile. (*) Values calculated by averaging the results obtained against 100 randomly generated sets of comparable sizes