Skip to main content

Table 2 Entities, networks and communities overlap comparisons

From: Comparing Alzheimer’s and Parkinson’s diseases networks using graph communities structure

A) Common entities  
  Alzheimer     
Alzheimer - Parkinson    
Parkinson 12 % - Influenza   
Influenza 8 % 8 % - mTOR  
mTOR 6 % 8 % 3 % - Random*
Random* 0.17 % 0.11 % 0.28 % 0.02 % -
B) Common interactions  
  Alzheimer     
Alzheimer - Parkinson    
Parkinson 81 % - Influenza   
Influenza 69 % 68 % - mTOR  
mTOR 77 % 86 % 64 % - Random*
Random* 8.83 % 7.7 % 8.97 % 3.5 % -
C) Similar communities  
  Alzheimer     
Alzheimer - Parkinson    
Parkinson 36 % - Influenza   
Influenza 28 % 27 % - mTOR  
mTOR 35 % 39 % 22 % - Random*
Random* 0.66 % 1.18 % 0.15 % 2.47 % -
  1. A) shows the percentage of common entities among the four lists analyzed calculated with Jaccard distance. B) Shows the overlap in terms of links between the four induced networks analyzed calculated with Hamming similarity. C) shows results obtained counting overlapping community pairs that have a functional similarity that falls in the fifth quintile. (*) Values calculated by averaging the results obtained against 100 randomly generated sets of comparable sizes