Table 1 Parameters for sensitivity analysis and validation. The effects of these parameters were examined by setting each to 10 %, 50 %, and 200 % of their baseline values, which are indicated here. The final column provides values used for validation with laboratory data

Probability of conidia lodging in epithelium

p _lodge

0.05

0.0223

Macrophage / neutrophil fungal detection radius

d e t_r a d i u s

15 μ m

11.67μ m

Diffusion rate for iron and cytokines

d i f f u s i o n_r a t e

0.5

0.397

Cytokine production factor

c y t o_r a t e

100

100

Maximum iron acquirable by fungus

i r o n _max (f)

2.5

3.633

Proportion of iron absorbed by fungus

i r o n_a b s(f)

0.5

0.76

Iron needed for fungal growth

i r o n _min (f)

0.25

0.9096

Cytokine absorption rate by macrophages / neutrophils

c y t o_a b s o r b

0.05

0.05

Cytokine recruitment threshold for macrophages / neutrophils

recr

5

5