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Fig. 4 | BMC Systems Biology

Fig. 4

From: A novel mathematical model of ATM/p53/NF- κB pathways points to the importance of the DDR switch-off mechanisms

Fig. 4

Impact of IR and TNF α on cells viability. a Percentage of cells viability for Ctr-RNAi and Wip1-RNAi cells after treatment with various doses of IR. b Percentage of Ctr-RNAi and Wip1-RNAi apoptotic cells 24 and 48 h after irradiation with various doses of IR. c Impact of TNF α on fraction size of apoptotic cells. Note: Because all p-values > 0.05 (for α=0.05), most of them > 0.85, there is no reason to reject the null hypothesis that experimental and simulation values are no different

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