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Table 1 The minimal sets of control nodes for the reverse control

From: Attractor landscape analysis of colorectal tumorigenesis and its reversion

APC
mutation
APC + KRAS
mutations
APC + KRAS + PTEN
mutations
APC + KRAS + PTEN + TP53
mutations
Control direction
Control nodes for a quiescent phenotype
beta-catenin beta-catenin beta-catenin beta-catenin
P115RhoGEF P115RhoGEF P115RhoGEF P115RhoGEF
MEK MEK MEK MEK
PP2A PP2A PP2A PP2A
Control nodes for a normal proliferative phenotype  
beta-arrestin beta-arrestin beta-arrestin beta-arrestin
Erk Erk Erk Erk
P115RhoGEF P115RhoGEF P115RhoGEF P115RhoGEF
Smad2/4 Smad2/4 Smad2/4 Smad2/4
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