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Table 2 Prediction on archived GOA files using BMA (see Eq. (4))

From: Interspecies gene function prediction using semantic similarity

  

MicroAvgF1

MacroAvgF1

1-RankLoss

Fmax

RAccuracy

CC

H →H

0.8328

0.7203

0.8780

0.8747

0.1542

 

M →H

0.8368

0.7125

0.8751

0.8750

0.1602

 

M+H →H

0.8586

0.7639

0.9808

0.8787

0.2844

 

D →H

0.8316

0.7197

0.8729

0.8738

0.1536

 

D+H →H

0.8524

0.7236

0.9068

0.8625

0.2530

 

A →H

0.8259

0.7068

0.8632

0.8532

0.1369

 

A+H →H

0.8363

0.7222

0.8797

0.8773

0.1717

 

M →M

0.7712

0.6084

0.8588

0.8571

0.1936

 

H →M

0.7676

0.6192

0.8580

0.8339

0.1864

 

H+M →M

0.8161

0.6590

0.9548

0.8637

0.3518

 

D →M

0.7718

0.6105

0.8416

0.8082

0.1868

 

D+M →M

0.8003

0.6160

0.8926

0.8315

0.2963

 

A →M

0.7660

0.6341

0.8444

0.8404

0.1761

 

A+M →M

0.7713

0.6143

0.8606

0.8523

0.1942

MF

H →H

0.8523

0.8179

0.9192

0.8915

0.1416

 

M →H

0.8513

0.8170

0.9145

0.8905

0.1311

 

M+H →H

0.8692

0.8372

0.9720

0.9029

0.2399

 

D →H

0.8502

0.8174

0.9123

0.8909

0.1295

 

D+H →H

0.8668

0.8355

0.9523

0.8742

0.2259

 

A →H

0.8416

0.8207

0.8964

0.8968

0.0793

 

A+H →H

0.8490

0.8151

0.9116

0.8894

0.1227

 

M →M

0.7654

0.6849

0.8755

0.8656

0.1344

 

H →M

0.7601

0.6821

0.8797

0.8545

0.1396

 

H+M →M

0.7784

0.7081

0.9248

0.8779

0.1801

 

D →M

0.7607

0.6891

0.8592

0.8369

0.1287

 

D+M →M

0.7841

0.7072

0.9200

0.8580

0.2013

 

A →M

0.7534

0.6880

0.8553

0.8607

0.0876

 

A+M →M

0.7639

0.6716

0.8712

0.8551

0.1264

BP

H →H

0.8373

0.7979

0.9507

0.8012

0.2044

 

M →H

0.8346

0.7943

0.9489

0.7981

0.1912

 

M+H →H

0.8450

0.8055

0.9690

0.8381

0.2421

 

D →H

0.8368

0.8027

0.9568

0.8031

0.2020

 

D+H →H

0.8368

0.7978

0.9496

0.8093

0.2018

 

A →H

0.8290

0.7903

0.9239

0.7799

0.1641

 

A+H →H

0.8325

0.7839

0.9308

0.7944

0.1809

 

M →M

0.7812

0.6965

0.9350

0.7905

0.1855

 

H →M

0.7842

0.6987

0.9401

0.7863

0.1965

 

H+M →M

0.7947

0.7134

0.9609

0.8270

0.2357

 

D →M

0.7816

0.7036

0.9348

0.7885

0.1867

 

D+M →M

0.7830

0.7108

0.9423

0.7875

0.1923

 

A →M

0.7768

0.6929

0.9027

0.7594

0.1692

 

A+M →M

0.7779

0.6871

0.9183

0.7807

0.1733

  1. H →H directly uses GO annotations of Human to predict annotations of Human genes. M →H only employs annotations of genes from Mouse to predict annotations of Human genes. M+H →H uses GO annotations of genes from Mouse and Human to predict annotations of Human genes. D+H →H uses annotations of genes from Danio rerio and Human to predict annotations of Human genes. A+H →H uses annotations of genes from Arabidopsis thaliana and Human to predict annotations of Human genes. M →M, H+M →M, D+M →M and A+M →M follow the similar protocol, but predict annotations of Mouse genes. The data in boldface is the statistically significant best among these comparing methods for a particular target species, and the significance is checked by paired t-test at 95% confidence intervals
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BMC Systems Biology

ISSN: 1752-0509

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