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Table 2 GO analysis in the HSN network

From: MORO: a Cytoscape app for relationship analysis between modularity and robustness in large-scale biological networks

Category

GO Terms

The largest module

The rest of genes

P-value

No. of genes %

No. of genes %

Cellular component

Cytoplasm

161

20.33

767

16.49

0.00794

Nucleus

230

29.04

531

11.42

0

Protein complex

26

3.28

83

1.79

0.0054

Molecular Function

Protein binding

249

31.44

1115

23.97

0.00001

Metal ion binding

85

10.73

351

7.55

0.00227

Nucleotide binding

58

7.32

234

5.03

0.00814

DNA binding

127

16.04

150

3.23

0

Biological Process

Gene expression

40

5.05

139

2.99

0.00263

Viral process

38

4.80

132

2.84

0.00338

Regulation of transcription, DNA-templated

115

14.52

177

3.81

0

  1. GO terms which are significantly enriched between the largest module and the rest of modules are listed. All P-values are calculated by using a z-test