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Table 2 The summary of sensitivities for the four compared methods under different significant levels (α) and proportions of reproducible genes (γ)

From: Quantitative reproducibility analysis for identifying reproducible targets from high-throughput experiments

  The proposed Method The copula mixture method [10] Benjamini & Heller method [9] The rank product method [8]
  α=0.1 α=0.05 α=0.1 α=0.05 α=0.1 α=0.05 α=0.1 α=0.05
γ=80% 0.992(0.0014) 0.991(0.0016) 0.948(0.0881) 0.905(0.1184) 0.97(0.0027) 0.96(0.0031) 0.754(0.0055) 0.687(0.0045)
γ=60% 0.99(0.002) 0.988(0.0021) 0.978(0.0071) 0.956(0.0119) 0.966(0.0028) 0.955(0.0033) 0.878(0.0052) 0.836(0.0058)
γ=40% 0.989(0.0024) 0.987(0.0024) 0.975(0.0069) 0.937(0.0161) 0.962(0.0046) 0.951(0.005) 0.949(0.0045) 0.931(0.0051)
γ=20% 0.985(0.0037) 0.983(0.004) 0.176(0.0149) 0.069(0.0081) 0.949(0.007) 0.937(0.0076) 0.978(0.0046) 0.972(0.0053)
γ=10% 0.984(0.0048) 0.982(0.0051) 0.421(0.1033) 0.228(0.0746) 0.934(0.0098) 0.92(0.0108) 0.985(0.0053) 0.982(0.0055)
γ=5% 0.984(0.0069) 0.983(0.0075) 0.773(0.0741) 0.509(0.0832) 0.925(0.0191) 0.909(0.0195) 0.99(0.0049) 0.988(0.0057)
γ=1% 0.986(0.0176) 0.984(0.0177) 0.907(0.0592) 0.842(0.0882) 0.866(0.0673) 0.844(0.0706) 0.99(0.0163) 0.99(0.0163)