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Fig. 10 | BMC Systems Biology

Fig. 10

From: Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions

Fig. 10

The waves 1, 3 and 5 runs as the purple, green and red lines respectively, for the 18 model outputs of interest. The targets for the history match given by the intervals z i ±3σ i , are shown as the black error bars, and the previous best run found by [30] is shown as the light blue line. The horizontal black line at zero represents no trend. We see that the history match has proceeded as expected, with the runs from subsequent waves getting closer and closer to the target data, resulting in a large number of acceptable wave 5 runs in red, that possess a better match quality than the previous best run

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