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Fig. 5 | BMC Systems Biology

Fig. 5

From: Network pharmacological mechanisms of Vernonia anthelmintica (L.) in the treatment of vitiligo: Isorhamnetin induction of melanogenesis via up-regulation of melanin-biosynthetic genes

Fig. 5

Effects of Isorhamnetin and Kaempferide on tyrosinase activity and melanin-biosynthetic genes in B16F10 melanoma cells. Effects of Isorhamnetin on tyrosinase activity in B16F10 melanoma cells (a). Quantified RT-PCR (QPCR) results in Isorhamnetin treatment via relative gene expression ratios to GAPDH (b). Effects of Kaempferide on tyrosinase activity in B16F10 melanoma cells (c). Quantified RT-PCR (QPCR) results in Kaempferide treatment via relative gene expression ratios to GAPDH (d). Data shown are the means ± standard errors of at least 3 independent experiments performed in triplicate. * P < 0.05 vs. the control, # P < 0.05 vs. 8-MOP (100 μM)

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